PrimePCR™ ddPCR™ Expression Probe Assay: F7, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027569; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049190
Chromosome Location:   13:113768173-113770035question
Amplicon Length:   134

Gene Information

This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by either factor IXa factor Xa factor XIIa or thrombin by minor proteolysis. Upon activation of the factor VII a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq Jul 2008]

Gene Symbol:   F7
Gene Name:   coagulation factor VII (serum prothrombin conversion accelerator)
Aliases:   Not Available
RefSeq:   NC_000013.10 NG_009258.1 NG_009262.1 NT_027140.6
Ensembl:   ENSG00000057593
Entrez:   2155
UniGene:   Hs.36989
Chromosome Mapping:   13q34

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