PrimePCR™ ddPCR™ Expression Probe Assay: DENND1A, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027503; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049068
Chromosome Location:   9:126429313-126439010question
Amplicon Length:   108

Gene Information

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010 [PubMed 20154091]).[supplied by OMIM Nov 2010]

Gene Symbol:   DENND1A
Gene Name:   DENN/MADD domain containing 1A
Aliases:   FAM31A, FLJ38464, KIAA1608, RP11-230L22.3
RefSeq:   NC_000009.11 NT_008470.19
Ensembl:   ENSG00000119522
Entrez:   57706
UniGene:   Hs.568340
Chromosome Mapping:   9q33.3

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