PrimePCR™ ddPCR™ Expression Probe Assay: TAB3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027413; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048921
Chromosome Location:   X:30873638-30877693question
Amplicon Length:   102

Gene Information

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein and the similar and functionally redundant protein MAP3K7IP2/TAB2 forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described but their biological validity has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   TAB3
Gene Name:   TGF-beta activated kinase 1/MAP3K7 binding protein 3
Aliases:   MAP3K7IP3, MGC45404, NAP1
RefSeq:   NC_000023.10 NG_012845.1 NT_167197.1
Ensembl:   ENSG00000157625
Entrez:   257397
UniGene:   Hs.188256
Chromosome Mapping:   Xp21.2

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