PrimePCR™ ddPCR™ Expression Probe Assay: SMARCA4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027403; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048908
Chromosome Location:   19:11130332-11132474question
Amplicon Length:   90

Gene Information

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI which is required for transcriptional activation of genes normally repressed by chromatin. In addition this protein can bind BRCA1 as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   SMARCA4
Gene Name:   SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Aliases:   BAF190, BRG1, FLJ39786, RTPS2, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, hSNF2b
RefSeq:   NC_000019.9 NG_011556.1 NT_011295.11
Ensembl:   ENSG00000127616
Entrez:   6597
UniGene:   Hs.327527
Chromosome Mapping:   19p13.2

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