PrimePCR™ ddPCR™ Expression Probe Assay: UHRF1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027346; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048823
Chromosome Location:   19:4929374-4930774question
Amplicon Length:   132

Gene Information

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   UHRF1
Gene Name:   ubiquitin-like with PHD and ring finger domains 1
Aliases:   FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000034063
Entrez:   29128
UniGene:   Hs.108106
Chromosome Mapping:   19p13.3

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