PrimePCR™ ddPCR™ Expression Probe Assay: METAP2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027228; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048640
Chromosome Location:   12:95879687-95887920question
Amplicon Length:   130

Gene Information

This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq Jul 2008]

Gene Symbol:   METAP2
Gene Name:   methionyl aminopeptidase 2
Aliases:   MAP2, MNPEP, p67, p67eIF2
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000111142
Entrez:   10988
UniGene:   Hs.444986
Chromosome Mapping:   12q22

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