PrimePCR™ ddPCR™ Expression Probe Assay: NOB1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027193; Intron-spanning

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048584
Chromosome Location:   16:69786173-69788558question
Amplicon Length:   134

Gene Information

In yeast over 200 protein and RNA cofactors are required for ribosome assembly and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S 5.8S and 25S rRNAs folding of the rRNA and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein 2009 [PubMed 19706509]).[supplied by OMIM Nov 2010]

Gene Symbol:   NOB1
Gene Name:   NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
Aliases:   ART-4, MST158, NOB1P, PSMD8BP1
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000141101
Entrez:   28987
UniGene:   Hs.271695
Chromosome Mapping:   16q22.3

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