PrimePCR™ ddPCR™ Expression Probe Assay: RASAL1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027179; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048565
Chromosome Location:   12:113543604-113544967question
Amplicon Length:   121

Gene Information

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but in contrast to the other GAP1 family members this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq Jul 2010]

Gene Symbol:   RASAL1
Gene Name:   RAS protein activator like 1 (GAP1 like)
Aliases:   RASAL
RefSeq:   NC_000012.11 NT_009775.17
Ensembl:   ENSG00000111344
Entrez:   8437
UniGene:   Hs.528693
Chromosome Mapping:   12q23-q24

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