PrimePCR™ ddPCR™ Expression Probe Assay: CTPS2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027050; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048327
Chromosome Location:   X:16717151-16720936question
Amplicon Length:   113

Gene Information

The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq Jan 2009]

Gene Symbol:   CTPS2
Gene Name:   CTP synthase II
Aliases:   DKFZp686C17207, FLJ43358, MGC32997
RefSeq:   NC_000023.10 NT_167197.1 NG_013229.1
Ensembl:   ENSG00000047230
Entrez:   56474
UniGene:   Hs.227049
Chromosome Mapping:   Xp22

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