PrimePCR™ ddPCR™ Expression Probe Assay: CENPF, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026952; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5048162
Chromosome Location:   1:214822128-214825141question
Amplicon Length:   102

Gene Information

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase respectively and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq Jul 2008]

Gene Symbol:   CENPF
Gene Name:   centromere protein F, 350/400kDa (mitosin)
Aliases:   CENF, PRO1779, hcp-1
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000117724
Entrez:   1063
UniGene:   Hs.497741
Chromosome Mapping:   1q32-q41

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