This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026896; Intron-spanning
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents and hence neuronal excitability in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jul 2008]