PrimePCR™ ddPCR™ Expression Probe Assay: PDE6A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026095; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5046646
Chromosome Location:   5:149240467-149242773question
Amplicon Length:   130

Gene Information

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha beta and two gamma subunits. cGMP is an important regulator of rod cell membrane current and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq Jul 2008]

Gene Symbol:   PDE6A
Gene Name:   phosphodiesterase 6A, cGMP-specific, rod, alpha
Aliases:   CGPR-A, PDEA, RP43
RefSeq:   NC_000005.9 NG_009102.1 NT_029289.11
Ensembl:   ENSG00000132915
Entrez:   5145
UniGene:   Hs.567314
Chromosome Mapping:   5q31.2-q34

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