PrimePCR™ ddPCR™ Expression Probe Assay: CHIT1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0058464; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5046121
Chromosome Location:   1:203194805-203197664question
Amplicon Length:   168

Gene Information

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq Jan 2012]

Gene Symbol:   CHIT1
Gene Name:   chitinase 1 (chitotriosidase)
Aliases:   CHI3, CHIT, FLJ00314, MGC125322
RefSeq:   NC_000001.10 NG_012867.1 NT_004487.19
Ensembl:   ENSG00000133063
Entrez:   1118
UniGene:   Hs.201688
Chromosome Mapping:   1q31-q32

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