PrimePCR™ ddPCR™ Expression Probe Assay: ITCH, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0058417; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5046041
Chromosome Location:   20:33095670-33095818question
Amplicon Length:   119

Gene Information

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Mar 2012]

Gene Symbol:   ITCH
Gene Name:   itchy E3 ubiquitin protein ligase homolog (mouse)
Aliases:   AIF4, AIP4, NAPP1, dJ468O1.1
RefSeq:   NC_000020.10 NG_023206.1 NT_011362.10
Ensembl:   ENSG00000078747
Entrez:   83737
UniGene:   Hs.632272
Chromosome Mapping:   20q11.22

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