PrimePCR™ ddPCR™ Expression Probe Assay: ABCB1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0058075; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5045426
Chromosome Location:   7:87148771-87150178question
Amplicon Length:   69

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq Jul 2008]

Gene Symbol:   ABCB1
Gene Name:   ATP-binding cassette, sub-family B (MDR/TAP), member 1
Aliases:   ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-GP, PGY1
RefSeq:   NC_000007.13 NG_011513.1 NT_007933.15
Ensembl:   ENSG00000085563
Entrez:   5243
UniGene:   Hs.489033
Chromosome Mapping:   7q21.12

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