PrimePCR™ ddPCR™ Expression Probe Assay: DYNLL1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057923; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5045186
Chromosome Location:   12:120936038-120936149question
Amplicon Length:   82

Gene Information

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1200 kD. They contain two force-producing heads formed primarily from dynein heavy chains and stalks linking the heads to a basal domain which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer a conformation necessary for activity and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   DYNLL1
Gene Name:   dynein, light chain, LC8-type 1
Aliases:   DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, MGC126137, MGC126138, PIN, hdlc1
RefSeq:   NC_000012.11 NT_009775.17
Ensembl:   ENSG00000088986
Entrez:   8655
UniGene:   Hs.5120
Chromosome Mapping:   12q24.23

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