PrimePCR™ ddPCR™ Expression Probe Assay: SFTPC, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0057801; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5045055
Chromosome Location:   8:22019377-22020181question
Amplicon Length:   72

Gene Information

This gene encodes the pulmonary-associated surfactant protein C (SPC) an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA SPB SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified which cause pulmonary surfactant metabolism dysfunction type 2 also called pulmonary alveolar proteinosis due to surfactant protein C deficiency and are associated with interstitial lung disease in older infants children and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq Feb 2010]

Gene Symbol:   SFTPC
Gene Name:   surfactant protein C
Aliases:   PSP-C, SFTP2, SMDP2, SP-C
RefSeq:   NC_000008.10 NT_167187.1 NG_016968.1
Ensembl:   ENSG00000168484
Entrez:   6440
UniGene:   Hs.1074
Chromosome Mapping:   8p21

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