PrimePCR™ ddPCR™ Expression Probe Assay: GMNN, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057753; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044964
Chromosome Location:   6:24786098-24786246question
Amplicon Length:   119

Gene Information

This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1 preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq Oct 2011]

Gene Symbol:   GMNN
Gene Name:   geminin, DNA replication inhibitor
Aliases:   Gem, RP3-369A17.3
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000112312
Entrez:   51053
UniGene:   Hs.234896
Chromosome Mapping:   6p22.3

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