This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0057749; exonic
Gamma-aminobutyric acid (GABA) receptors are a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA the major inhibitory neurotransmitter in the mammalian brain acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates benzodiazepines and ethanol (summary by Whiting et al. 1999 [PubMed 10414349]). For additional general information about the GABA-A receptor gene family see GABRA1 (MIM 137160).[supplied by OMIM Dec 2009]