PrimePCR™ ddPCR™ Expression Probe Assay: NAE1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0057728; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044919
Chromosome Location:   16:66839824-66839927question
Amplicon Length:   74

Gene Information

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8 a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   NAE1
Gene Name:   NEDD8 activating enzyme E1 subunit 1
Aliases:   A-116A10.1, APPBP1, ula-1
RefSeq:   NC_000016.9 NT_010498.15
Ensembl:   ENSG00000159593
Entrez:   8883
UniGene:   Hs.460978
Chromosome Mapping:   16q22

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