PrimePCR™ ddPCR™ Expression Probe Assay: GLI2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057630; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044738
Chromosome Location:   2:121748442-121748588question
Amplicon Length:   117

Gene Information

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome Pallister-Hall syndrome preaxial polydactyly type IV postaxial polydactyly types A1 and B. [provided by RefSeq Jul 2008]

Gene Symbol:   GLI2
Gene Name:   GLI family zinc finger 2
Aliases:   HPE9, THP1, THP2
RefSeq:   NC_000002.11 NG_009030.1 NT_022135.16
Ensembl:   ENSG00000074047
Entrez:   2736
UniGene:   Hs.111867
Chromosome Mapping:   2q14

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