PrimePCR™ ddPCR™ Expression Probe Assay: IL7R, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0057619; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044717
Chromosome Location:   5:35876996-35877145question
Amplicon Length:   120

Gene Information

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor gamma chain (IL2RG) which is a common gamma chain shared by the receptors of various cytokines including interleukine 2 4 7 9 and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq Jul 2008]

Gene Symbol:   IL7R
Gene Name:   interleukin 7 receptor
Aliases:   CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
RefSeq:   NC_000005.9 NG_009567.1 NT_006576.16
Ensembl:   ENSG00000168685
Entrez:   3575
UniGene:   Hs.591742
Chromosome Mapping:   5p13

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