PrimePCR™ ddPCR™ Expression Probe Assay: PPFIBP1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057524; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044566
Chromosome Location:   12:27788033-27800671question
Amplicon Length:   83

Gene Information

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4 a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   PPFIBP1
Gene Name:   PTPRF interacting protein, binding protein 1 (liprin beta 1)
Aliases:   L2, SGT2, hSGT2, hSgt2p
RefSeq:   NC_000012.11 NT_009714.17
Ensembl:   ENSG00000110841
Entrez:   8496
UniGene:   Hs.172445
Chromosome Mapping:   12p12.1

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