PrimePCR™ ddPCR™ Expression Probe Assay: IL12RB1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057499; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044530
Chromosome Location:   19:18182997-18183135question
Amplicon Length:   109

Gene Information

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   IL12RB1
Gene Name:   interleukin 12 receptor, beta 1
Aliases:   CD212, IL-12R-BETA1, IL12RB, MGC34454
RefSeq:   NC_000019.9 NG_007366.1 NT_011295.11
Ensembl:   ENSG00000096996
Entrez:   3594
UniGene:   Hs.567294
Chromosome Mapping:   19p13.1

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