PrimePCR™ ddPCR™ Expression Probe Assay: SALL3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0056180; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044454
Chromosome Location:   18:76754341-76754495question
Amplicon Length:   125

Gene Information

This gene encodes a sal-like C2H2-type zinc-finger protein and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila C. elegans and vertebrates. Mutations in some of these genes are associated with congenital disorders in human suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A) and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene resulting in acceleration of DNA methylation may have a role in oncogenesis. [provided by RefSeq Oct 2011]

Gene Symbol:   SALL3
Gene Name:   sal-like 3 (Drosophila)
Aliases:   ZNF796
RefSeq:   NC_000018.9 NT_025028.14 NW_003315961.1
Ensembl:   ENSG00000256463
Entrez:   27164
UniGene:   Hs.700557
Chromosome Mapping:   18q23

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