PrimePCR™ ddPCR™ Expression Probe Assay: HBB, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0056072; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044290
Chromosome Location:   11:5246721-5246831question
Amplicon Length:   81

Gene Information

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq Jul 2008]

Gene Symbol:   HBB
Gene Name:   hemoglobin, beta
Aliases:   CD113t-C, beta-globin
RefSeq:   NC_000011.9 NG_000007.3 NT_009237.18
Ensembl:   ENSG00000244734
Entrez:   3043
UniGene:   Hs.523443
Chromosome Mapping:   11p15.5

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