PrimePCR™ ddPCR™ Expression Probe Assay: PCDHAC2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0056047; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044251
Chromosome Location:   5:140347950-140348088question
Amplicon Length:   109

Gene Information

This gene is a member of the protocadherin alpha gene cluster one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons or variable exons are followed by downstream C-terminal exons or constant exons which are shared by all genes in the cluster. The large uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq Jul 2008]

Gene Symbol:   PCDHAC2
Gene Name:   protocadherin alpha subfamily C, 2
Aliases:   MGC71598, PCDH-ALPHA-C2
RefSeq:   NC_000005.9 NG_000016.2 NT_029289.11
Ensembl:   ENSG00000243232
Entrez:   56134
UniGene:   Not Available
Chromosome Mapping:   5q31

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