PrimePCR™ ddPCR™ Expression Probe Assay: EXOSC6, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055944; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5044075
Chromosome Location:   16:70284197-70284303question
Amplicon Length:   77

Gene Information

This gene product constitutes one of the subunits of the multisubunit particle called exosome which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known however it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs) but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs thereby promoting their rapid degradation. [provided by RefSeq Jul 2008]

Gene Symbol:   EXOSC6
Gene Name:   exosome component 6
Aliases:   EAP4, MTR3, Mtr3p, hMtr3p, p11
RefSeq:   NC_000016.9 NG_023191.1 NT_010498.15
Ensembl:   ENSG00000223496
Entrez:   118460
UniGene:   Hs.461187
Chromosome Mapping:   16q22.1

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