PrimePCR™ ddPCR™ Expression Probe Assay: TREX1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055854; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043905
Chromosome Location:   3:48508553-48508702question
Amplicon Length:   120

Gene Information

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome chilblain lupus and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   TREX1
Gene Name:   three prime repair exonuclease 1
Aliases:   AGS1, CRV, DKFZp434J0310, DRN3, HERNS
RefSeq:   NC_000003.11 NG_009820.1 NT_022517.18
Ensembl:   ENSG00000213689
Entrez:   11277
UniGene:   Hs.707026
Chromosome Mapping:   3p21.31

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