PrimePCR™ ddPCR™ Expression Probe Assay: MLLT11, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055837; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043881
Chromosome Location:   1:151040087-151040224question
Amplicon Length:   108

Gene Information

The gene variously symbolized ALL1 HRX or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue this gene was expressed in all leukemic cell lines tested. [provided by RefSeq Jul 2008]

Gene Symbol:   MLLT11
Gene Name:   myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
Aliases:   AF1Q, RP11-316M1.10
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000213190
Entrez:   10962
UniGene:   Hs.75823
Chromosome Mapping:   1q21

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