PrimePCR™ ddPCR™ Expression Probe Assay: DENND1C, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055789; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043790
Chromosome Location:   19:6478954-6479686question
Amplicon Length:   91

Gene Information

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1C function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010 [PubMed 20154091]).[supplied by OMIM Nov 2010]

Gene Symbol:   DENND1C
Gene Name:   DENN/MADD domain containing 1C
Aliases:   FAM31C, FLJ22757
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000205744
Entrez:   79958
UniGene:   Hs.236449
Chromosome Mapping:   19p13.3

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