PrimePCR™ ddPCR™ Expression Probe Assay: IPO7, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055765; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043756
Chromosome Location:   11:9431483-9431603question
Amplicon Length:   91

Gene Information

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors namely importin beta itself transportin RanBP5 and RanBP7 directly bind and import ribosomal proteins. [provided by RefSeq Jul 2008]

Gene Symbol:   IPO7
Gene Name:   importin 7
Aliases:   FLJ14581, Imp7, MGC138673, RANBP7
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000205339
Entrez:   10527
UniGene:   Hs.701236
Chromosome Mapping:   11p15.4

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