PrimePCR™ ddPCR™ Expression Probe Assay: PRMT6, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055655; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043568
Chromosome Location:   1:107600605-107600743question
Amplicon Length:   109

Gene Information

The protein encoded by this gene belongs to the arginine N-methyltransferase family which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both the formation of omega-N monomethylarginine and asymmetrical dimethylarginine with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3 and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with and methylates DNA polymerase beta resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq Sep 2011]

Gene Symbol:   PRMT6
Gene Name:   protein arginine methyltransferase 6
Aliases:   FLJ10559, FLJ51477, HRMT1L6
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000198890
Entrez:   55170
UniGene:   Hs.26006
Chromosome Mapping:   1p13.3

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