This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055655; exonic
The protein encoded by this gene belongs to the arginine N-methyltransferase family which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both the formation of omega-N monomethylarginine and asymmetrical dimethylarginine with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3 and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with and methylates DNA polymerase beta resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq Sep 2011]