PrimePCR™ ddPCR™ Expression Probe Assay: CD3E, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055646; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043552
Chromosome Location:   11:118186540-118186652question
Amplicon Length:   83

Gene Information

The protein encoded by this gene is the CD3-epsilon polypeptide which together with CD3-gamma -delta and -zeta and the T-cell receptor alpha/beta and gamma/delta heterodimers forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq Jul 2008]

Gene Symbol:   CD3E
Gene Name:   CD3e molecule, epsilon (CD3-TCR complex)
Aliases:   FLJ18683, T3E, TCRE
RefSeq:   NC_000011.9 NG_007383.1 NT_033899.8
Ensembl:   ENSG00000198851
Entrez:   916
UniGene:   Hs.3003
Chromosome Mapping:   11q23

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