PrimePCR™ ddPCR™ Expression Probe Assay: GRM3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055639; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043538
Chromosome Location:   7:86394356-86394500question
Amplicon Length:   115

Gene Information

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology putative signal transduction mechanisms and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4 GRM6 GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq Jul 2008]

Gene Symbol:   GRM3
Gene Name:   glutamate receptor, metabotropic 3
Aliases:   GLUR3, GPRC1C, MGLUR3, mGlu3
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000198822
Entrez:   2913
UniGene:   Hs.590575
Chromosome Mapping:   7q21.1-q21.2

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