PrimePCR™ ddPCR™ Expression Probe Assay: UNC13B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055613; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043490
Chromosome Location:   9:35310763-35313980question
Amplicon Length:   71

Gene Information

This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq Jul 2008]

Gene Symbol:   UNC13B
Gene Name:   unc-13 homolog B (C. elegans)
Aliases:   MGC133279, MGC133280, MUNC13, UNC13, Unc13h2, hmunc13
RefSeq:   NC_000009.11 NT_008413.18
Ensembl:   ENSG00000198722
Entrez:   10497
UniGene:   Hs.493791
Chromosome Mapping:   9p13.3

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