PrimePCR™ ddPCR™ Expression Probe Assay: YTHDF2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055579; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043436
Chromosome Location:   1:29068983-29069112question
Amplicon Length:   100

Gene Information

This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene which is thought to be associated with human longevity. In addition reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14 which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq Mar 2010]

Gene Symbol:   YTHDF2
Gene Name:   YTH domain family, member 2
Aliases:   HGRG8, NY-REN-2
RefSeq:   NC_000001.10 NT_004610.19 NG_016746.1
Ensembl:   ENSG00000198492
Entrez:   51441
UniGene:   Hs.532286
Chromosome Mapping:   1p35

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