PrimePCR™ ddPCR™ Expression Probe Assay: NTRK1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055570; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043420
Chromosome Location:   1:156845344-156845886question
Amplicon Length:   100

Gene Information

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that upon neurotrophin binding phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain anhidrosis self-mutilating behavior mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found but only three have been characterized to date. [provided by RefSeq Jul 2008]

Gene Symbol:   NTRK1
Gene Name:   neurotrophic tyrosine kinase, receptor, type 1
Aliases:   DKFZp781I14186, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
RefSeq:   NG_016849.1 NC_000001.10 NG_007493.1 NT_004487.19
Ensembl:   ENSG00000198400
Entrez:   4914
UniGene:   Hs.406293
Chromosome Mapping:   1q21-q22

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