PrimePCR™ ddPCR™ Expression Probe Assay: CARD11, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055558; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5043396
Chromosome Location:   7:2987235-2987350question
Amplicon Length:   86

Gene Information

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10 a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq Jul 2008]

Gene Symbol:   CARD11
Gene Name:   caspase recruitment domain family, member 11
Aliases:   BIMP3, CARMA1, MGC133069
RefSeq:   NC_000007.13 NG_027759.1 NT_007819.17
Ensembl:   ENSG00000198286
Entrez:   84433
UniGene:   Hs.648101
Chromosome Mapping:   7p22

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