PrimePCR™ ddPCR™ Expression Probe Assay: EIF4EBP1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055194; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042730
Chromosome Location:   8:37917632-37917778question
Amplicon Length:   117

Gene Information

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq Jul 2008]

Gene Symbol:   EIF4EBP1
Gene Name:   eukaryotic translation initiation factor 4E binding protein 1
Aliases:   4E-BP1, 4EBP1, BP-1, MGC4316, PHAS-I
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000187840
Entrez:   1978
UniGene:   Hs.411641
Chromosome Mapping:   8p12

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