PrimePCR™ ddPCR™ Expression Probe Assay: DCC, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055164; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042674
Chromosome Location:   18:50936838-50936962question
Amplicon Length:   95

Gene Information

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq Oct 2009]

Gene Symbol:   DCC
Gene Name:   deleted in colorectal carcinoma
Aliases:   CRC18, CRCR1, IGDCC1
RefSeq:   NC_000018.9 NG_013341.1 NT_010966.14
Ensembl:   ENSG00000187323
Entrez:   1630
UniGene:   Hs.162025
Chromosome Mapping:   18q21.3

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