PrimePCR™ ddPCR™ Expression Probe Assay: EPOR, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0055163; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042672
Chromosome Location:   19:11488476-11488619question
Amplicon Length:   114

Gene Information

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq May 2010]

Gene Symbol:   EPOR
Gene Name:   erythropoietin receptor
Aliases:   EPO-R, MGC138358
RefSeq:   NC_000019.9 NG_021395.1 NT_011295.11
Ensembl:   ENSG00000187266
Entrez:   2057
UniGene:   Hs.631624
Chromosome Mapping:   19p13.3-p13.2

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