PrimePCR™ ddPCR™ Expression Probe Assay: INSIG1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0055100; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042567
Chromosome Location:   7:155100244-155100385question
Amplicon Length:   112

Gene Information

Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq Jun 2009]

Gene Symbol:   INSIG1
Gene Name:   insulin induced gene 1
Aliases:   CL-6, CL6, MGC1405
RefSeq:   NC_000007.13 NT_007741.14
Ensembl:   ENSG00000186480
Entrez:   3638
UniGene:   Hs.520819
Chromosome Mapping:   7q36

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