PrimePCR™ ddPCR™ Expression Probe Assay: GP1BA, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054992; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042376
Chromosome Location:   17:4836868-4836979question
Amplicon Length:   82

Gene Information

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer an alpha chain and a beta chain that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury and also initiates signaling events within the platelet that lead to enhanced platelet activation thrombosis and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq Mar 2010]

Gene Symbol:   GP1BA
Gene Name:   glycoprotein Ib (platelet), alpha polypeptide
Aliases:   BSS, CD42B, CD42b-alpha, GP1B, MGC34595
RefSeq:   NC_000017.10 NG_008767.2 NT_010718.16
Ensembl:   ENSG00000185245
Entrez:   2811
UniGene:   Hs.1472
Chromosome Mapping:   17pter-p12

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