PrimePCR™ ddPCR™ Expression Probe Assay: DUSP8, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054940; exonic

 
Fluorophore:   FAM
List Price:    $201.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042288
Chromosome Location:   11:1575741-1575830question
Amplicon Length:   60

Gene Information

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK SAPK/JNK p38) which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases different tissue distribution and subcellular localization and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38 is expressed predominantly in the adult brain heart and skeletal muscle is localized in the cytoplasm and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq Jul 2008]

Gene Symbol:   DUSP8
Gene Name:   dual specificity phosphatase 8
Aliases:   C11orf81, FLJ42476, FLJ42958, HB5, HVH-5, HVH8
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000184545
Entrez:   1850
UniGene:   Hs.41688
Chromosome Mapping:   11p15.5

Number Description Download
10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
10033173 ddPCR™ Copy Number Variation Assays Product Insert, Ver C Click to download
10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
10047489 ddPCR™ Mutation Detection Assays Product Insert, Ver B Click to download
10048730 PrimePCR™ ddPCR™ Gene Expression Probe Assays Product Insert, Rev A Click to download