This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054873; exonic
MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 22.214.171.124). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al. 2007 [PubMed 17604280]).[supplied by OMIM Apr 2010]