PrimePCR™ ddPCR™ Expression Probe Assay: KLRC4, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054863; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042147
Chromosome Location:   12:10562227-10562354question
Amplicon Length:   98

Gene Information

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K member 1) family member. [provided by RefSeq Dec 2010]

Gene Symbol:   KLRC4
Gene Name:   killer cell lectin-like receptor subfamily C, member 4
Aliases:   FLJ17759, FLJ78582, NKG2-F, NKG2F
RefSeq:   NC_000012.11 NT_009714.17
Ensembl:   ENSG00000183542
Entrez:   8302
UniGene:   Hs.721094
Chromosome Mapping:   12p13.2-p12.3

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