PrimePCR™ ddPCR™ Expression Probe Assay: SLC8A1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054827; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5042084
Chromosome Location:   2:40657235-40657341question
Amplicon Length:   77

Gene Information

In cardiac myocytes Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM Apr 2004]

Gene Symbol:   SLC8A1
Gene Name:   solute carrier family 8 (sodium/calcium exchanger), member 1
Aliases:   DKFZp779F0871, FLJ37694, FLJ43417, MGC119581, NCX1
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000183023
Entrez:   6546
UniGene:   Hs.468274
Chromosome Mapping:   2p23-p22

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