PrimePCR™ ddPCR™ Expression Probe Assay: CDH4, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054616; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041714
Chromosome Location:   20:60498757-60503248question
Amplicon Length:   120

Gene Information

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Nov 2011]

Gene Symbol:   CDH4
Gene Name:   cadherin 4, type 1, R-cadherin (retinal)
Aliases:   CAD4, FLJ22202, FLJ40547, MGC126700, MGC138355, RCAD
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000179242
Entrez:   1002
UniGene:   Hs.473231
Chromosome Mapping:   20q13.3

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