PrimePCR™ ddPCR™ Expression Probe Assay: GLDC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054571; exonic

Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041631
Chromosome Location:   9:6532786-6532916question
Amplicon Length:   101

Gene Information

Degradation of glycine is brought about by the glycine cleavage system which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase) H protein (a lipoic acid-containing protein) T protein (a tetrahydrofolate-requiring enzyme) and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq Jan 2010]

Gene Symbol:   GLDC
Gene Name:   glycine dehydrogenase (decarboxylating)
Aliases:   GCE, GCSP, HYGN1, MGC138198, MGC138200
RefSeq:   NC_000009.11 NG_016397.1 NT_008413.18
Ensembl:   ENSG00000178445
Entrez:   2731
UniGene:   Hs.584238
Chromosome Mapping:   9p22

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